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List of Lectins and Specificity
Lectin specificity

How to use this list:
The following list shows the glycan binding specificity of the lectins used as ligands. Please select the carbohydrate structure you want to separate. Then choose an appropriate lectin or a combination of lectins from the list. You will find a variety of products in the list beside for each of the displayed lectins.


 Lectin  Name  Organism  Affinity *)
Mannose binding lectins
Con A Concanavalin A Canavalia ensiformis branched α -mannosidic structures;
high-mannose type, hybrid type and biantennary complex type N-Glycans
LCH Lentil lectin Lens culinaris Fucosylated core region of bi- and triantennary complex type N-Glycans
GNA Snowdrop lectin Galanthus nivalis α 1-3 and α 1-6 linked high mannose structures
Galactose / N-acetylgalactosamine binding lectins
ECL Coral Tree Erythrina cristagalli Galβ1-4GlcNAcβ1-R
PNA Peanut Agglutinin Arachis hypogaea Galβ1-3GalNAcα1-Ser/Thr (T-Antigen)
AIL Jacalin Artocarpus integrifolia (Sia)Galβ1-3GalNAcα1-Ser/Thr (T-Antigen)
VVL Hairy vetch lectin Vicia villosa GalNAcα-Ser/Thr (Tn-Antigen)
Sialic acid / N-acetylglucosamine binding lectins
WGA Wheat Germ agglutinin Triticum vulgaris GlcNAcβ1-4GlcNAcβ1-4GlcNAc, Neu5Ac (sialic acid)
SNA Elderberry lectin Sambucus nigra Neu5Acα2-6Gal(NAc)-R
MAL Maackia amurensis lectin Maackia amurensis Neu5Ac/Gcα2-3Galβ1-4GlcNAcβ1-R
Fucose binding lectins
UEA Ulex europaeus agglutinin Ulex
europaeus
Fucα1-2Gal-R
AAL Aleuria aurantia lectin Aleuria aurantia Fucα1-2Galβ1-4(Fucα1-3/4)Galβ1-4GlcNAc;
R2-GlcNAcβ1-4(Fucα1-6)GlcNAc-R1

* To get a general overview only basic structural information is demonstrated. For details please contact our technical support or see the cited literature. The structures represent only examples for a binding event. Often lectins bind with high affinity to complex and multiantennary saccharide structures.
more lectins
Literature

Gabius, H.-J.; Gabius, S. (Eds.): Glycosciences - Status and Perspectives. Weinheim: Chapman & Hall, 1997. ISBN 3-8261-0073-5

Goldstein, I. J.; Poretz, R. D.: Isolation, Physicochemical Characterization, and Carbohydrate-Binding Specificity of Lectins. In: Liener, I. E.; Sharon, N.; Goldstein, I. J. ( Eds.) The Lectins - Properties, Functions and Applications in Biology and Medicine. Orlando: Academic Press, 1986, S. 33-243.

Debray, H.; Decout, D.; Strecker, G.; Spik, G.; Montreuil, J. (1981): Specificity of Twelve Lectins Towards Oligosaccharides and Glycopeptides Related to N-Glycosylproteins. Eur. J. Biochem., 117, 41-55.
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